A BRIEF NOTE FROM PAKISTAN: REFLECTIONS FROM A BRITISH PSYCHIATRIST



TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Abstract Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure.We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced maladaptive cardiac fibrosis by forming stably functional complex with NADPH oxidase 2 (Nox2).Although TR

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Role of RBC labeled 99m-Tc scan, Histopathology and Immunohistochemistry in Diagnosis of Jejunal Gastrointestinal Stromal Tumor presenting as obscure gastrointestinal haemorrhage

Gastrointestinal stromal tumors (GIST) are relatively rare tumors of gastrointestinal (GI) tract, most commonly arise from the stomach followed by small intestine and colon, clinically GIST present with occult GI bleeding, abdominal pain and intestinal obstruction.We present Accessory a case of a jejunal GIST, which presented as an obscure GI haemo

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